Chemical messengers which travel in the blood to activate target cells
What are endocrine glands?
Ones which secrete hormones into the blood to reach the target organ
What are 8 examples of endocrine glands?
1. Endocrine pancreas
2. Testes
3. Ovaries
4. Pituitary gland
5. Thyroid gland
6. Pineal gland
7. Adrenal gland
8. Thymus
What are gonads?
Reproductive organs
What are 3 examples of hormones made by the pituitary gland?
1. Growth hormone
2. ADH
3. Gonadotropins
What does growth hormone do?
Stimulates bone and muscle growth
What does ADH do?
Increases water reabsorption in the kidneys
What do gonadotropins do?
Control development of the sex organs
What does the pineal gland produce?
Melatonin
What does melatonin do?
Controls sleep/wake cycles and affects reproductive development
What does the Thyroid gland produce?
Thyroxine
What does thyroxine do?
Controls rate of metabolism and rate at which glucose is used up in respiration, as well as promoting growth
What does the thymus produce?
Thymosin
What does thymosin do?
Promotes the proliferation and maturation of T cells
What 2 hormones are produced by the endocrine pancreas?
Glucagon and insulin
What hormone do the testes produce?
Testosterone
What does testosterone do?
Influences sperm cell development and also produces the male secondary sex characteristics
What 2 hormones do the ovaries produce?
1. Estrogen
2. Progesterone
What does estrogen do?
Creates secondary sex characteristics in the female and controls ovulation
What does progesterone do?
Maintains lining of uterus
What are the 2 types of hormone?
Steroid and non-steroid
What are target cells?
Cells that have receptors for a particular hormone
What is an example of a steroid hormone?
Estrogen
What is an example of a non-steroid hormone?
Adrenaline
What differentiates how steroid and non-steroid hormones behave?
Steroid hormones are lipid-soluble and pass through the plasma membrane of the target cells, but non-steroid hormones are not lipid-soluble and so must bind to receptors on their cell surface membrane
What happens when a steroid hormone passes into a target cell?
It binds to a receptor to form a hormone-receptor complex, which then acts as a transcription factor for a specific gene
What 2 places in the cell can steroid hormone receptors be found?
Nucleus and cytoplasm
How do non-steroid hormones work?
They bind to a cell-surface receptor which causes a cascade reaction within the cell mediated by secondary messengers
Which of neuronal and hormonal communication is quicker?
Neuronal
Which of neuronal and hormonal communication is longer-lasting?
Hormonal
What is the difference between hormonal and neuronal communication in terms of how widespread the response is?
Neuronal tends to be localised, hormonal is much more widespread (although limited to target organs)
What is the difference between hormonal and neuronal communication in terms of whether the response is temporary or permanent?
Neuronal tends to be temporary, hormonal can be temporary but can also be permanent
What is the difference between hormonal and neuronal communication in terms of the reversibility of the response?
Neuronal tends to be reversible, hormonal can have irreversible effects
What are the 3 parts of the adrenal gland?
Capsule, cortex, medulla
Where in the body are the adrenal glands found?
On top of the kidneys
What is the functional of the adrenal glands' capsule?
It is a protective membrane layer
What 3 types of hormone are produced by the adrenal medulla?
1. Glucocortisoids
2. Mineralocortisoids
3. Androgens
What androgens are produced by the adrenal medulla?