Myasthenia gravis

• What is Myasthenia gravis

  autoimmune disorders causes severe muscle weakness
• characterized by

  period of exacerbation and remission
• Immune system attacking and blocking

  acetylcholine receptors at neuromascular junction
• signs and symptoms worst at

  excercise and improve with rest
• Other sign and symptoms

  Diplopia Dysphagia SOB thymus hyperplasia
• what thymus produces

  T cells
• Others Diagnostic procedure

  Electromyography repitative nerve stimulation test
• Diagnostic test

  endrophonium or tensilon test
• what purpose of edrophonium test

  to deffirentiate mystenia gravis and cholinergic crisis
• edeophonium cholinergic to increase

  acetylcholine and help patien with symptoms
• treatment

  cholinergics agent neostigmine pyridostigmine and immunosuppressant prednisone , plasmapheresis