Efavirenz

• What are the indications are efavirenz?

  HIV
• What are the side effects of efavirenz?

  Diarrhoea

  Nausea

  Headache
• What is the pharmacology of efavirenz?

  Target: Reverse transcriptase

  Activity: Antagonist
• What is efavirenz?

  Non-nucleoside reverse transcriptase inhibitor
• MOA - efavirenz

  Inhibits reverse transcriptase -> no generation of DNA from HIV RNA -> no synthesis of new HIV proteins -> no HIV replication