Tenofovir disoproxil fumarate

Cards (5)

  • What are the indications of tenofovir disoproxil fumarate?
    HIV
    Chronic hepatitis B
  • What are the side effects of tenofovir disoproxil fumarate?
    Diarrhoea
    Neutropenia
    Vomiting
  • What is tenofovir disoproxil fumarate?
    Nucleotide analogue reverse transcriptase inhibitor
  • What is the pharmacology of tenofovir disoproxil fumarate?
    Target: Reverse transcriptase
    Activity: Antagonist
  • MOA - tenofovir disoproxil fumarate
    Blocks reverse transcriptase -> no conversion of HIV RNA to DNA -> no viral proteins produced -> reduced viral load