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HIV
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Tenofovir disoproxil fumarate
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Created by
Jessica Jardine
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Cards (5)
What are the indications of tenofovir disoproxil fumarate?
HIV
Chronic hepatitis B
What are the side effects of tenofovir disoproxil fumarate?
Diarrhoea
Neutropenia
Vomiting
What is tenofovir disoproxil fumarate?
Nucleotide analogue reverse transcriptase inhibitor
What is the pharmacology of tenofovir disoproxil fumarate?
Target:
Reverse transcriptase
Activity:
Antagonist
MOA - tenofovir disoproxil fumarate
Blocks
reverse transcriptase
->
no conversion
of
HIV RNA
to
DNA
->
no viral proteins
produced ->
reduced viral load