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Third Quarter Grade 8
Biotechnology: Third Quarter
History Of DNA and RNA
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DNA
&
RNA
- They are known as the
nucleic acids
which are responsible for
genetics
DNA - The acronym for
Deoxyribo Nucleic Acid
Friedrich Miescher
- the first person that identified the DNA as an acidic substance present in the Nucleus
James Watson
&
Francis Crick
- they described the DNA as a
double helix strand
Albrecht Kossel
- he isolated the nucleic acids (Adenine, Thymine, Cytosine, Guanine)
Linus Pauling
- he discovered the spiral structure of proteins
Rosalind Franklin (same lab as
Maurice Wilkins
) -she studied the x-ray diffraction of the DNA
Rosalind Franklin
- she found out that the DNA is Helical, More than one strand, and has more than 10 pairs
DNA
- is found at the center of the cell (NUCLEUS) and is made up of
two strands
of nucleotides
DNA - is often divided into four different levels:
primary
,
secondary
,
territory
, and
quartermary
DNA has three components:
Deoxyribose
(propose sugar),
Nucleotides
(bases: Adenine, Cytosine, Guanine, Thymine), and
Phosphate
(salt)
The nucleotides are divided into two groups (THE NITROGIOUS):
Pyramidines
and
Purines
Pyramidines
(6 member ring) - Thymine and Cytosine (1 ring)
Purines
(6 member ring) - Adenine and Guanine (2 rings)
Structure of Nucleotides - formed from the
condensation
of a
sugar-phosphate
and one of the
4 bases
Shape of the Deoxyribose -
pentagon
RNA - is a single stranded molecule that is found at the
cytoplasm
RNA
- the acronym for Ribonucleic Acid
Ribose
- the sugar component for RNA
RNA
- cannot replicate itself because it needs the help of DNA and other cellular components
Messenger RNA
(mRNA) - a type of RNA that contains the instruction that direct cells to make proteins
Transfer RNA
(tRNA) - a type of RNA that carries the amino acids into the ribosome
Ribosomal RNA
(rRNA) - forms the ribosomes
The RNA has four bases:
Adenine
,
Cytosine
,
Guanine
and
Uracil