Module 7: Regulation

• how does regulation begin in general?

  signal molecule transport
• what does recognition of signal molecule cause?

  change in gene and enzyme behavior
• what are the 3 types of regulation?

  1. post translational regulation
  2. translational regulation
  3. transcriptional regulation (gene expression)
• is regulation specific or nonspecific?

  specific
• is regulation rapid or slow response?

  rapid response
• is regulation an on/off switch?

  no, up/down tuning of equilibrium
• allosteric proteins: modified by interactions with other molecules
• allosteric site is seperate from active site
• binding of allosteric effector changes enzyme activity
• what are the 4 common mechanisms of regulation in bacteria?

  1. whether mRNA is made
  2. RNA stability
  3. protein stability
  4. protein function