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Topic 1
6. atherosclerosis and blood clotting
blood clotting
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ellie
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what can a blood clot be known as?
thrombus
process of blood clotting?
damage to
endothelium
of artery= platelets attach
prothrombin
(enzyme) released from platelets/damages tissue
enzyme in presence of
calcium ions
and
vitamin K
converts
thromboplastin
-> thrombin (enzyme)
thrombin:
fibrinogen
-> fibrin, forming mesh of insoluble fibres
mesh traps red blood cells and platelets, forming a blood clot.
what is a platelet?
type of
blood cell
with
no nucleus
, flares up and sticks to
exposed collagen
what is thromboplastin?
soluble
enzyme
, catalyses conversion of
prothrombin
-> thrombin
what is prothrombin?
soluble
plasma
protein
what is thrombin?
enzyme
that converts
fibrinogen
-> fibrin
what is fibrinogen?
soluble
plasma protein
what is fibrin?
insoluble
fibrous
protein, forms mesh to trap
red blood cells