connective tissue

• special CT

  skeleton, blood, fat
• ordinary CT

  ligaments, tendons, stroma
• components of ct

  extracellular matrix and cells
• cells in connective tissue

  fibroblasts and white blood cells
• extracellular matrix components

  ground substance: water, GAGs, and fibres
• fibroblasts

  actively synthesising and secrete ECM
• fibrocytes

  mature fibroblasts that maintain ECM
• fibroblasts

  lots of rER, lots of golgi
• fibrocytes

  little rER and little golgi
• collagen synthesis

  amino acids, fibroblasts (with vitamin c and enzymes), collagen molecule, collagen fibre
• type one collagen

  ordinary CT and bone, strongest and most abundant
• type 2 collagen

  mostly hyaline cartilage
• type 3 collagen

  reticular fibres
• type 4 collagen

  basal lamina
• type 5 collagen

  muscle and tendon sheaths
• fibroblasts make elastic fibres and ground substance
• loose CT

  delicate, good for movement, much ground substance, few fine fibres
• Dense Ct

  strong, good for resisting stretch, little ground substance, many bundles of fibres
• dense CT can be:

  collagenous (typical) or elastic (unusual), regular (tendon) or irregular (reticular dermis)
• why does loose ct need lots of cells

  exposed to many microorganisms, needed for immune response
• function of loose CT

  diffusion
• dense CT function

  strength and mechanical support
• where is the elastic lamina found

  aorta, subclavian, brachiocephalic
• what does adipose tissue consist of

  adipocytes tightly packed together
• adipocyte appearance

  large lipid droplet filling cytoplasm, with the nucleus being pushed to the extremities
• where are adipocytes found

  loose and dense irregular CT
• adipose tissue function

  support tissue, shock absorption, energy store
• brown adipose tissue appearance

  multilocar, numerous mitochondria
• BAT function

  metabolises fat to produce heat in infants
• embryonic CT

  mesenchyme and mucus connective tissue
• collagen fibres form extracellularly
• in LCT< fibres are always irregular
• LCT has a mix of all fibre types