biological therapy

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    Created by
    Hannah Masters

    Cards (6)

    • chlorpromazine
      • typical (1st gen)
      • linked to original DA hypothesis
      • produced in 1950s
      • dosages of 400-800, maximum of 1000mg
      • tablet, syrup or injection
      • dopamine antagonist, reduced DA activity in synaptic receptors
      • used for sedation and to stop hallucinations
      • side effects:low mood an relaxation
    • clozapine
      • more common than chlorpromazine
      • atypical
      • 1970s, as typical wasn't working for sz
      • dosages os 300-450mg daily
      • not taken as injection due to lethal blood condition caused
      • dopamine, glutamate and seratonin antagonist
      • side effects: improved mood, good for suicidal patients
      • not much as a sedative as chlorpromazine
    • risperidone
      • atypical
      • 1990s, used to avoid Lethal blood condition caused by clozapine
      • dosages of 4-8mg daily
      • taken as Tabley, syrup and injection
      • dopamine and serotonin antagonist
      • lower dosage means less side effects
    • supporting evidence
      • research support for effectiveness
      • Thornley supports effectiveness as in 13 trials taking typical had less severe side effects than the placebo group
      • Meltzer found atypical (clozapine) was effective in 30-50% of treatment resistant cases when typical antipsychotics didn't work
    • limitation
      • serious side effects
      • typical are associated with urinary and sexual dysfunction
      • atypical are associated with weight gain and heart problems
      • suggest long term, antipsychotics may not be suitable as they can result in facial tics
      • fatal side effects of lethal blood condition which means people avoid taking treatments, making them ineffective
    • real world application
      • strength
      • if someone is having a severe psychotic episode, injecting them with chlropromazine to sedate and relieve symptoms is highly effective
      • also, by using typical as a sedative, people become more calm are more likely to engage in their other treatments (therapy)
      • counterpoint - chemical cosh argument, antipsychotics can be human rights abuse (moncrieff 2013). to administer sedative drugs in different dosages is abuse of human rights
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