How does immunological comparisons of proteins work?
Serum from species A injected into species B
Species B produces antibodies specific to species A antigens
Serum extracted from species B, contains the antibodies
Serum from B is mixed with serum from blood of species C
Antibodies respond to corresponding antigen on albumin
response forms a precipitate
Greater number of similar antigens more precipitate is formed and more closely related species is