Ribosomes are responsible for protein synthesis in the cell.
DNA is located in the nucleus of the cells apart from red blood cells
DNA is inherited - passed on from generation to generation
DNA is the genetic material of living things
DNA is a long chemical sequence and this
sequence contains the information for that
living thing to develop, survive and pass on its
genetic information to the next generation.
The DNA chemical sequence differs between
individuals. The pattern of this sequence is
called the genotype.
The sum total of all genetic information of
an individual is the genome.
DNA contains the genetic information (code)
to make the specific proteins required by a
cell.
Proteins determine a cell’s structure,
allowing it to perform its function (allowing
the cells to differentiate)
Copies of the cell’s genetic information are
passed onto daughter cells during cell division
Copies of a cell’s genetic information is
passed on to the next generation when
gametes fuse during fertilisation – the genetic
code is inherited.
Proteins contain the elements
carbon, hydrogen, oxygen and
nitrogen
Proteins are large, insoluble
molecules made up of a chain of
smaller molecules called amino
acids of which there are 20 types.
Amino acids are joined together by
peptide bonds.
Structural proteins build proteins that form hair and cell membranes
Enzymes speed up the rate of chemical reactions such as photosynthesis and respiration that are essential for life
Hormones are chemical messengers eg insulin
antibodies defend against antigens
DNA has two strands
coiled into a double helix.
Each strand of DNA is made up of nucleotides
Nucleotides are made up of three components: phosphate, deoxyribose and nitrogenous base
The deoxyribose sugar is a pentose sugar –
meaning it contains 5 carbons.
Nucleotides are linked by their deoxyribose sugars and phosphates to form a strand with a sugar-phosphate backbone.
DNA has 4 nitrogenous bases.
Two strands of nucleotides are connected by hydrogen bonds between complementary base pairs.
Adenine pairs with thymine and cytosine pairs with guanine
The two DNA strands connect running in opposite directions
Organisms fall into two main categories: prokaryotes and eukaryotes
DNA is found in the cytoplasm in the form of a large singular circular chromosome or smaller rings called plasmids
Prokaryotic cells also do NOT have membrane bound organelles [chloroplasts or mitochondria]
Prokaryotic chromosomes have no introns and eukaryotic chromosomes have introns
Small circular rings of DNA are found in the chloroplasts and mitochondria of eukaryotic cells
Mitochondria are found in the cytoplasm of cells including ova
The mitochondria genes code from the enzymes of aerobic respiration so mutations can be lethal
Yeast is a unicellular fungus
Yeast cells are unusual as they also contain some circular plasmids in their cytoplasm similar to those found in prokaryotes
DNA replication ensures that an exact copy of a species genetic information is passed on from cell to cell during growth and from generation to generation during reproduction
Each strand of DNA acts as a template for a new complementary strand so each DNA molecule formed during replication would be identical, each containing one ‘parental’ strand and one newly synthesised strand
When the DNA in a chromosome is being replicated, many replication forks are formed at the same time. As a result, the DNA of whole chromosomes is replicated quickly and precisely
Leading strand – replication of DNA from the 3’ end is continuous moving towards the replication fork