Crisostomo Ibarra - a Filipino who studied in Europe for 7 years, the main character of the novel and the love interest of Maria Clara
Elias - Ibarra's mysterious friend, a fugitive
Maria Clara - Ibarra's sweetheart; the illegitimate daughter of Padre Damaso and Pia Alba
Padre Damaso - a Franciscan friar and Maria Clara's biological father
Linares - Maria Clara's would-be fiancé; a distant nephew of Don Tiburcio
Sisa - mother of Crispin and Basilio, who went insane after losing her sons
Crispin - the younger son of Sisa who died at the hands of the soldiers
Basilio - the elder son of Sisa
Kapitan Tiago - also known as Don Santiago de los Santos, the known father of Maria Clara
Padre Salvi - described as thin, sickly and silent; a secret admirer of Maria Clara
Pilosopo Tasio - an intelligent pessimistic old man
Don Filipo - close relative of Ibarra and a filibuster
The Alferez - mortal enemy of the priests for the power in San Diego
Don Tiburcio - a charlatan who is limp and submissive to his wife
Doña Victorina - a woman who passes herself off as one of the Peninsulares; wife of Don Tiburcio
Doña Consolacion - wife of the Alferez; also passes herself off as a Peninsular
Pedro - abusive husband of Sisa; loves cockfighting