CB2- Mitosis

• Mitosis is the nuclear division producing 2 genetically identical daughter cells
• Interphase is when normal metabolic activity takes place and the DNA replicates itself
• Prophase - DNA condenses and spindle fibers form. Nuclear membrane breaks down.
• Metaphase - chromosomes line up along equator of cell
• Anaphase - sister chromatids separate at center of cell and move towards opposite poles via spindle fibers
• Telophase - nuclear membrane reform . The DNA unravels and the spindle fibers break down
• Cytokinesis - splitting of cytoplasm
• Mitosis is important for: growth, repair of damaged cells and to asexually reproduce.
• Mitosis ensures that cells divide only when they need to and stop when required.
• Cancer - mutations in the DNA of cells leading to uncontrolled cell division forming lumps called a tumor.
• Benign tumors - non cancerous growth of abnormal cells, confined to a specific area.
• malignant tumors - cancerous growth of abnormal cells which can spread throughout the body