The global transfer of goods, flora, fauna, cultural practices, and disease between the Old World and the New World as a result of European imperialism
Smallpox and other diseases from Europe devastated indigenous populations in the Americas, leading to the "Great Dying" where populations plummeted by up to 90%
High-yielding and nutrient-packed foods like maize, tomatoes, potatoes, and cacao from the Americas went to Europe, while foods like rice and wheat from Europe went to the Americas, changing their diets and improving health
Gold and silver plundered from the Inca and Aztec empires made Spain incredibly wealthy, hastening the end of feudalism and the rise of capitalism in Europe
An economic and social system imposed by the Spanish in the Americas, where Spaniards could by law exact tribute and labor from indigenous Americans, degenerating into a form of slavery