Possession of the skull or cranium which protects the brain and sense organs, Cartilage in all the embryos (chondrocranium), changed to a bony skull (osteocranium) in the adult
Possess a notochord, embryonic condition, replaced by the vertebral column in the adult
The epidermis becomes a stratified epithelium, Mucous glands in aquatic forms, Cornified in terresterial forms
The pharynx is provided with gill slits, embryonic condition, continue in aquatic forms and replaced by lungs, The mouth contains a tongue and usually teeth
The circulatory system is closed and a heart of three chambers at least, The blood contains red and white blood corpuscles, Haemoglobin pigment is present
Presence of true coelom, divided into pericardial cavity and perivisceral cavity
Presence of two kidneys with two ureters
Presence one pair of gonads (except Petromyzon) provided with genital ducts carrying their products