When you are well and maintaining your body well, the maintaining of the internal environment of our body
Disease
The body functions working differently then normal
Homeostasis
When the body prevents the external environment from changing the internal environment
If homeostasis is not maintained in the internal environment, cells may not get everything they need or toxic wastes may accumulate in cells, eventually leading to diseases
Keeping The Body In Balance
1. When you get too hot, you sweat
2. When you get too cold, you shiver
Shiver
Muscles contract and relax, helping you warm up
Sweat
Water evaporates, and the skin surface cools down
The cells that make up our bodies function best in certain conditions. The body's ability to maintain a stable state despite these changes is called homeostasis
The body needs to also keep its levels of sugar, salt and water. A key role is played by hormones
Blood Glucose Levels
1. If there is too much glucose, a hormone instructs target cells in the liver and muscles, called insulin, produced by the pancreas
2. If the body cannot use insulin effectively, it causes a health condition called diabetes
3. If the level of blood glucose gets too low, the pancreas releases a different hormone called glucagon. This hormone instructs cells to release glucose into the blood
Type 1 Diabetes
Pancreas cannot produce enough insulin to control blood glucose levels. People may need regular injections of insulin to help meet needs
Type 2 Diabetes
The target cells of insulin stop responding properly. It's also called insulin resistance, and it can often be treated by a change of diet
Feedback Loops
1. When a hormone is sent out into the body, the information is received and therefore affects other responses in the body
2. The rate of hormone production and secretion is often regulated using negative feedback loops
3. If a stimulus is received indicating that a hormone effect is happening too much, the response would be to produce less of that hormone. This is a change in a system that causes another change that brings it back to the starting position, and it is used to maintain homeostasis
Infectious disease
A disease caused by a pathogen which can be transmitted between people
Pathogens
Bacteria
Viruses
Fungi
Protozoa
Microparasites
Prion
Bacteria
Prokaryotic (no membrane bound organelles)
Viruses
Non-living (acellular)
Fungi
Eukaryotic (have membrane-bound organelles)
Healthy
In a good physical or mental condition, in good health
Bacteria
Can quickly replicate in our bodies, killing cells. It can also produce toxins which can kill cells and cause an outsized, damaging immune reaction
Virus
Can get into someone's body, and produce clones of itself, overtaking other cells and infecting the body
Fungi
Specific fungi can reproduce 'spores' particles that can enter our body through the lungs or skin. It can spread quickly and damage many organs. Other fungal infections can be caused by an overgrowth of commensal fungus
Bacteria
Single celled organisms without a nucleus, usually around 0.2µm in diameter. Diseases can include strep throat, staph infections, tuberculosis, food poisoning, tetanus, pneumonia, syphilis
Virus
Non living particles that reproduce by taking over other cells, usually around 20-200nm. Diseases include common cold, flu, genital herpes, cold sores, measles, AIDs, chicken pox
Fungi
Simple organisms that grow as single cells or thread like filaments, usually 2-10µm in diameter. Diseases include ringworm, athlete's foot, tineas, candidiasis, histoplasmosis, mushroom poisoning
Protozoa
Single celled organisms with a nucleus, usually less than 50µm. Diseases can include Maralea, 'traveller's diarrhoea', giardiasis, trypanosomiasis, sleeping sickness
Microparasites
Multicellular organisms that do not multiply within the final host, usually can be seen with the naked eye. Diseases include nematodes, tapeworms, ticks, flukes, fleas
Prion
Abnormal pathogenic agents and they are transmittable, usually around 30.35kDa. Diseases include Creutzfeldt-Jakob disease (CJD)
Contagious
When an infectious disease can pass from one person to another
Not all infectious diseases are contagious, a medical condition that cannot be spread from person to person is non-contagious. For a disease to be infectious, it needs to be caused by a pathogen
Transmission methods
Eating contaminated food or drinking contaminated water
Breathing in infected saliva droplets after someone coughs or sneezes
Exchanging bodily fluids, such as blood or saliva
By a vector, such as a mosquito or tick
Deadliness or virulence of a disease
The percentage of infected people that die from it
Contagiousness of a disease
How easily it spreads
Ways to prevent the spread of disease
Frequently wash your hands with soap
Avoid touching nose, eyes or mouth
Do not share cutlery with other people
Quarantine yourself if you are feeling unwell
Epidemiologist
A person who studies the branch of medicine which deals with the incidence, distribution and possible control of diseases
Epidemic
A more widespread outbreak that may affect the entire nation
Pandemic
An epidemic that is affecting the entire world
Endemic
An outbreak confined to a particular geographical area
Direct transmission
Occurs when there is physical contact between the infected person and the other person (skin-to-skin, herpes type 1)
Indirect contact
Occurs when there is no direct skin-to-skin contact (food-borne, salmonella)