4

• Substitution of bromine for hydrogen


  An overall exothermic process, but requires a catalyst to convert the bromine molecule into a more reactive electrophile
• Nitration reaction


  • A process wherein a nitro group is added in an organic compound.
• Positive result of nitration reaction


  • Yellow oily substance called Nitrobenzene
• Methyl benzoate


  • A methyl ester formed by the condensation of methanol & benzoic acid in the presence of strong acid.
  • Nitrating Methyl Benzoate with HNO3 using H2SO4 as catalyst.
  • Nitrating the Benzene ring is an electrophilic aromatic substitution reaction
• Medicinal/pharmaceutical use

  • Budesonide (Anti-inflammatory, Anti-asthma)
  • Chlorpromazine (Antipsychosis)
  • Paracetamol (Analgesic)
  • Ibuprofen (Anti-inflammatory, Pain reliever)
  • Chlorpheniramine (Antihistamine)
  • Amoxicillin (Antibiotic)
• Resorcinol


  Used as antiseptic and disinfectant in topical pharmaceutical products in treatment of skin disorders and infections
• Alkyl halides


  aka "haloalkanes", CH3 — X (X = halogen F,Cl,Br,I), Depending on the degree of substitution at the carbon atom carrying the halogen (primary, secondary, tertiary)