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psychopathology
biological approach
explaining OCD
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Cards (13)
genetic explanation of OCD
genes are involved in
individual
vulnerability to OCD
Lewis study
1936
observed that
37%
of his
PCD
patients had parents with
OCD
21%
of OCD patients had siblings with OCD
suggests OCD runs in the
family
diathesis-stress model
certain
genes
leave some people more likely to develop a mental
disorder
but it is not certain
some environmental stress is necessary to
trigger
the condition
candidate genes
candidate genes create vulnerability to OCD
some of these genes are involved in the regulation of the development of serotonin
e.g.
5HT1-D
is implicated in the transport of
serotonin
across synapses
OCD is polygenic
means OCD is not caused by one single gene but a combination of
genetic
variation that together increase vulnerability
Taylor research
2013
analysed findings of previous studies
found evidence of
up to 230
different
genes
that may be involved in OCD
genes associate with the action of
dopamine
and
serotonin
that are both believed to have a role in mood regulation
different types of OCD
genes
that cause OCD in one person may not cause OCD in another
aetiologically
heterogenous
= the origins of OCD vary from one person to another
strength of genetic explanation of OCD
strong
evidence base
strong evidence base
suggest that some people are vulnerable to
OCD
as a result of their
genetic
make-up
Nested et al
2010
reviewed twin studies
found
68%
of
identical twins
shared OCD as opposed to
31%
of
non-identical twins
suggests there is strong
genetic influence
libation of genetic explanation
environmental
risk factor
environmental risk factor
evidence that OCD does not appear to be entirely
genetic
environmental factors trigger or increase risk of OCD
in only genetic all
100%
of
identical twins
would share OCD
Cromer et al
2007
found that over half of
OCD
clients
in their sample had experience a
traumatic
event in their past
suggests
environmental factors
impact chances of OCD