Onc

Cards (32)

  • What is the earliest and most common symptom of vincristine use?
    Peripheral neuropathy
  • What condition is cisplatin associated with?
    Hypomagnesaemia and peripheral neuropathy
  • What is the most common type of lung cancer in non-smokers?
    Lung adenocarcinoma
  • What is the role of Carcinoembryonic Antigen (CEA) in colorectal cancer?
    Monitoring disease activity
  • What visual disturbances can SVC obstruction cause?
    Blurred vision
  • What marker should be included in the diagnostic work-up for abdominal malignancy in women?
    CA 125
  • Which lung cancer type has the strongest association with smoking?
    Squamous cell lung cancer
  • What should be suspected in a patient with new back pain and a history of cancer?
    Spinal metastasis
  • How can bone metastases present clinically?
    As pathological fractures
  • What is the most common cause of SVC obstruction?
    Small cell lung cancer
  • What should be administered if neoplastic spinal cord compression is suspected?
    High-dose oral dexamethasone
  • What is a tumour marker for medullary thyroid cancer?
    Calcitonin
  • What is the tumour marker associated with breast cancers?
    CA 15-3
  • In women with bone metastases, where is the cancer most likely to originate?
    Breast
  • Which mutation is associated with prostate cancer in men?
    BRCA2 mutation
  • What is the use of dexamethasone in patients with intracranial tumours?
    To suppress nausea and vomiting
  • What side effect may cisplatin cause?
    Ototoxicity
  • What serious lung condition can bleomycin cause?
    Pulmonary fibrosis
  • What cardiac issue can anthracyclines like doxorubicin cause?
    Cardiomyopathy
  • What side effects can methotrexate cause?
    Myelosuppression, mucositis, liver fibrosis
  • What side effects are associated with cyclophosphamide?
    Haemorrhagic cystitis and myelosuppression
  • What side effects can fluorouracil (5-FU) cause?
    Myelosuppression, mucositis, dermatitis
  • What side effect is associated with hydroxyurea?
    Myelosuppression
  • What tumour marker is associated with ovarian cancer?
    CA 125
  • What tumour marker is associated with pancreatic cancer?
    CA 19-9
  • What tumour marker is associated with hepatocellular carcinoma?
    Alpha-feto protein
  • What tumour marker is associated with teratoma?
    Alpha-feto protein
  • What is the association of HPV subtypes 6 and 11?
    Non-carcinogenic and associated with genital warts
  • What is the risk associated with HPV subtypes 16, 18, and 33?
    Increase the risk of cervical cancer
  • What is SVC obstruction classified as?
    An oncological emergency
  • What should patients with suspected neoplastic spinal cord compression undergo?
    An urgent MRI of the whole spine
  • What is the primary dose-limiting side effect of cisplatin?
    Nephrotoxicity