Roundworms, parasites that can cause disease in animals, plants, and humans
General morphology of nematodes
Nonsegmented
Cylindrical
Bilaterally symmetrical
Sexes are separate
No circulatory system
Complete digestive tract
Nematode life cycle
1. Egg
2. Larva
3. Adult
Nematodes can be subdivided into 3 major classifications: intestinal nematodes, vector-borne nematodes, and tissue-dwelling nematodes
Intestinal nematodes
Ascaris lumbricoides
Enterobius vermicularis
Trichuris trichiura
Capillaria philippinensis
Ancylostoma duodenale
Necator americanus
Strongyloides stercoralis
Strongyloides fuelleborni
Trichostrongylus spp.
Anisakis spp.
Vector-borne nematodes
Wuchereria bancrofti
Brugia malayi
Brugia timori
Loa loa
Mansonella ozzardi
Mansonella streptocerca
Mansonella perstans
Onchocerca volvulus
Dirofilaria spp.
Tissue-dwelling nematodes
Dracunculus medinensis
Trichinella spiralis
Toxocara canis
Toxocara cati
Enterobius vermicularis infection diagnosis
Finding eggs in perianal specimens
Infective stage of Trichuris trichiura in humans
Embryonated egg
Characteristics of L3 larva
It is the infective stage of Ancylostoma duodenale
It has a closed mouth
It is the feeding stage of the larva
It is also known as the filariform larva
Intestinal nematode that is larviparous
Capillaria philipinensis
Dental pattern of Ancylostoma duodenale
Semilunar cutting plates
Characteristics of Strongyloides stercoralis
Male S. stercoralis is parthenogenetic
Tail of the filariform larva is notched/forked
Rhabditiform larva has a small genital primordium
Causative agent of swollen belly syndrome/sickness
Strongyloides fuelleborni
Characteristics of Wuchereria bancrofti microfilaria
Irregularly spaced nucleus
Vector of Loa loa
Mango fly
Nematode commonly called the blinding worm
Onchocerca volvulus
Habitat of adult Trichinella spiralis worms
Striated muscles
Reagent for Knott's concentration technique
1 mL of blood + 10 mL of 2% formalin
Heartworm of dogs
Dirofilaria immitis
Mansonella ozzardi has a subperiodic microfilaria
Onchocerca volvulus has a nonperiodic microfilaria
Wuchereria bancrofti has a nocturnal microfilaria
Loa loa has a diurnal microfilaria
Female adult worm with a uterus having a characteristic barber's pole appearance
Trichuris trichiura
Brugia malayi microfilaria does not have two terminal nuclei
Schistosoma japonicum
Parasite that causes schistosomiasis
Schistosoma haematobium
Parasite that causes schistosomiasis
Schistosoma mekongi
Parasite that causes schistosomiasis
Schistosoma intercalatum
Parasite that causes schistosomiasis
Subcutaneous tissue, liver (sinusoids)
Locations where trematodes can be found
Mesenteric veins (vesical, prostatic or uterine veins: S. haematobium)
Locations where trematodes can be found
Trematodes, also known as flukes, are part of the phylum Platyhelminthes that can contribute infection to humans either by mechanical obstruction or local inflammatory mechanisms
Adult trematodes and eggs differ in general morphology and some differ in its life cycle and development
Larval stages of trematodes
1. Miracidium
2. Sporocyst
3. Redia
4. Cercaria
5. Metacercaria
Miracidium is the infective stage to the 1st intermediate host (snails) and metacercaria found in the 2nd intermediate host is the infective stage to the definitive host and is acquired by ingestion
For Schistosomal flukes, it is the cercaria that acts as infective stage that is transmitted by skin penetration
All trematodes require two intermediate hosts to complete its life cycle, except Schistosomes
All trematode eggs are operculated, except Schistosomes
All trematodes are hermaphrodite, except Schistosomes that are dioecious