The Proteome

Cards (5)

  • Genome
    Complete set of DNA
    Comprises of coding and non-coding regions
    20-25,000 genes in the human genome
  • Proteome
    Entire set of proteins that can be expressed from a genome
    250k-1 million proteins
    much larger than the genome
  • Intron
    Non-coding region of RNA
  • Exons
    Coding regions of RNA
  • Why is the proteome larger?

    Alternative RNA splicing
    Not all genes are expressed as proteins in a particular cell type.
    The set of proteins expressed by a given cell type can vary over time and under different conditions.
    Post-translational modification.