Monoclonal Antibodies

Cards (4)

  • 1.An antigen is injected into a mouse
    2.The mouse naturally produces lymphocytes, which produce antibodies specific to the antigen
    3.Spleen cells which produce the lymphocytes are removed during a small operation.
    4.The spleen cells are fused with human cancerous white blood cells called myeloma cells to form hybridoma cells which divide indefinitely and are grown in a laboratory.
    5.These hybridoma cells divide and produce millions of monoclonal antibodies specific to the original antigen which are then collected
  • What are monoclonal antibodies used for?
    Used for diagnosis, to measure levels of protein e.g. hormones in the blood, to identify molecules in a cell or tissue (fluorescence) and to treat e.g. cancer
  • Why are monoclonal antibodies used less than expected?
    Due to side effects
  • HCG is in antibody of pregnant woman which helps with pregnancy sticks as that determines if ur carrying a baby