got on her nerves - made her angry
despair - hopelessness,misery
antidote - cure,remedy,medicine
ingredient - component,element
concoct - create, formulate
distressed - upset,troubled,concerned
discreetly - subtly,without anyone/anything noticing
untwined - untwisted,unmoved,uncoiled
scabs - thick skin covering or coatings that are formed from healing wounds
flick - move sharply with a jerk
clapsing - holding tightly