ARENAVIRIDAE

• What is the primary reservoir for Lymphocytic Choriomeningitis Mammarenavirus (LCMV)?

  Mus musculus
• Which receptor is typically utilized by New World arenaviruses for cell entry?

  Transferrin receptor 1
• What is a potential consequence of intrauterine infection with LCMV in infants?

  Hydrocephalus, Chorioretinitis, Encephalomyelitis
• What is the primary mode of transmission of LCMV within wild Mus musculus populations?

  Vertical transmission
• Which antiviral drug may be beneficial in some patients with Lassa fever?

  Ribavirin
• Where was the Lujo virus first identified in 2008?

  Africa
• Reservoir host for Sabia virus.

  Rodents
• What is the most common method for serosurveillance of lymphocytic choriomeningitis virus in laboratory rodents?

  ELISA or Indirect immunofluorescence assay
• What year was Chapare virus isolated following a small cluster of cases near Cochabamba, Bolivia?

  2003
• What is the unique genome organization of Arenoviruses?

  Two segments of single-stranded RNA