Consists of values that support the alternative hypothesis Ha and leads to the rejection of null hypothesis Ho, with an area given by the level of significance α
If a nondirectional alternative hypothesis (Ha involving the quantified ≠) is formulated, the critical region is divided into two equal regions located in each tail of the distribution, each with an area of α/2
If a directional alternative hypothesis (Ha involving the quantifier > or <) is formulated, the critical region is concentrated on one tail of the distribution having an area of α
If a directional alternative hypothesis (Ha involving the quantifier >) is formulated, the critical region is located at the right-tail or upper-tail of the distribution
If a directional alternative hypothesis (Ha involving the quantifier <) is formulated, the critical region is located at the left-tail or lower-tail of the distribution