Antibodies

• what do all antibodies end in

  mab
• how does protein electrophoresis separate proteins by

  molecular weight
• what are the steps of binding for B cell maturation

  antigens bind to IgM and IgD
• fill in the blanks

  A) light chains

  B) C-termini

  C) heavy chains

  D) N-termini

  
• fill in the blanks

  .

  A) disulfide bond

  B) carbohydrate

  C) papain

  D) pepsin

  
• what do framework regions do

  intersperse CDRs
• what are the heavy chains

  IgD

  IgA
• what are the light chains

  kappa

  lambda
• where is IgD expressed

  monomeric naive B cells
• what is the role of IgD

  affinity maturation
• how many antibodies is IgE

  monomeric
• what activates IgE

  mast cells (allergies)
• what does IgE bind to

  Fc epsilon receptor
• what is the role of IgE

  mast cell degranulation
• how many antibodies is IgM

  pentameric
• what is the role of IgM

  antibacterial immune response
• how many antibodies is IgA

  dimeric
• what is the role of IgA

  mucosal immune response
• how many antibodies is IgG

  monomeric
• what is the role of IgG

  pass antibodies through placenta
• what is specificity

  ability of a molecule to recognise an epitope
• what is valency

  number of potential binding sites