To initiate an immune response, the pathogen must breach the host's barriers
Types of immunity
Innate
Adaptive
Innate immunity
Quick, generic response
Recognizes there is a threat and attacks
PRRs
Pattern recognition receptors on cell surface to recognize pathogen
Adaptive immunity
Very specific, recognizes exact strains
Memory response
Gets called in when innate can't deal with it alone
Clonal selection
Cells with right receptors are selected
Innate and adaptive immunity
Work together for a full immune response
Cytokines
Produced by innate immunity to stimulate and direct adaptive immunity
Adaptive immunity consists of B lymphocytes (B cells) that produce antibodies to neutralize or mark pathogens, and T lymphocytes (T cells) that recognize infected host cells and destroy them through cell-mediated immunity.
Tolerance
Ensures that the immune system avoids destroying host tissue
