1. Blood brings nutrients and removes wastes in tissue throughout the body
2. Oxygenated blood flows from left atrium to left ventricle and pumps into aorta
3. Passes from aorta to elastic arteries to muscle arteries before entering arterioles
4. Blood from arterioles enters systemic capillaries of trunk and lower limbs and systemic capillaries of head, neck, and upper limbs
5. Blood in arterioles enters capillaries for exchange of gases and nutrients
6. Deoxygenated blood exits capillary beds into venules and into veins
7. Deoxygenated blood conducted to either superior or inferior vena cava; enters right atrium of the heart