Thursday

• Compounds in table 1

  • Ascorbic acid
  • Phenol
  • Sodium bicarbonate
  • 2-naphthalammonium
• Nature


  • Weak acid
  • Weak acid
  • Weak base
  • Weak base
• pKa


  • 4.1
  • 9.8
  • 10.3
  • 4.6
• Ionisation of compounds at pH 3, 6 and 12

  Describe the ionisation
• Separating a solution containing Sodium bicarbonate and ascorbic acid

  Based on pKa, pH and ionisation, describe a method
• Water is the liquid of choice in car cooling systems
• Water is the liquid of choice in houses' central heating systems
• Rationale behind pharmaceutical companies formulating cefuroxime

  1. Cefuroxime Axetil tablets

  2. Cefuroxime sodium

  3. Cefuroxime Axetil oral suspension