Renal Tubular Cells

• RTE cells are RECTANGULAR, COLUMNAR, ROUND, OVAL or CUBOIDAL with an ECCENTRIC nucleus possibly stained with what?

  Bilirubin or hemosiderin-laden
• What is the SMALLEST EPITHELIAL CELL but is the MOST SIGNIFICANT?

  RTE cells
• Presence of RTE cells indicates what?

  Tubular injury
• PCT: larger, rectangular shape (columnar or convoluted), and coarsely granular cytoplasm
• DCT: smaller and round or oval
• Collecting Duct: CUBOIDAL and are NEVER ROUND
• The presence of RTE in collecting ducts are noticeable in cases of what?

  salicylate poisoning
• What is the reporting for RTE cells?

  Average/HPF
• Presence of RTE cells is indicative of necrosis of what?

  Renal tubules
• RTE cells: heavy metals, drug-induced toxicity, hemoglobin and myoglobin toxicity, viral infections (hepatitis B) etc
• RTE cells is secondary to what?

  glomerular disorders