Transcriptional Factors

• Transcriptional factors bind to genes and control protein synthesis and increased or decreased polypeptides produced impact whether genes are turned on or off.
• Transcriptional factors (proteins) bind to base sequences and initiate transcription of the gene (turned on).
• Oestrogen complementary to the binding site change the structure of the DNA binding site if they bind to it, now complementary DNA (activated transcriptional factor), RNA polymerase can now attach.