1511 = Creation of the holy league, anti-French alliance, Spain and HRE both involved.
1516 = FerdinandofAragon dies, Charles becomes the king of Spain and the HRE.
1517 = Treaty of Cambrai (F+S+HRE), England isolated.
1518 = Treaty of London, perpetual peace, ultimately insignificant but established henry as a peacemaker + Wolsey became papal legate.
1521 = Treaty of Bruges with Charles, sided with him over France, (more territory in France, pope relations + marriage) following the 1520 field of cloth of gold.
Charles V won against the French at the Battle of Pavia in 1525, Henry suggested joint invasion of France after, Charles declined and cancelled marriage with Princess Mary.
1527 = sackofRome, Pope controlled by Charles, led to treaty of Westminster in 1527.
Charles caused English unemployment due to trade embargo attempt by Henry.
Charles won the Battle of Landriano against France and Peace of Cambrai (between France and Spain/Hre) in 1529, doomed diplomatic aims for divorce.
Charles won the Battle of Landriano against the French and Peace of Cambrai in 1529, doomed diplomatic aims for divorce, no foreign support.