Blood flow kept moving by the pumping of the heart
Capillaries
Permit exchange of material with the tissues
Walls are one cell thick
Drain blood to venules
Extremely narrow
Contain shunts
Veins
Carry blood toward the heart
Largest holding capacity
Vena cava are the largest
Contain valves
Contain approximately 70% of blood
Act as a blood reservoir
All three blood vessel types have an inner endothelium, a simple squamous epithelium attached to a connective tissue basement membrane that has elastic fibres
Arterioles
Inner layer: endothelium
Middle layer: some elastic tissue but mostly smooth muscle
Outer layer: fibrous connective tissue
Smooth muscle in arterioles contracts
Blood vessel constricts, resulting in higher blood pressure
Smooth muscle in arterioles relaxes
Blood vessel relaxes, resulting in lower blood pressure
Capillaries
Composed of a single layer of epithelium with a basement membrane
Form vast networks (capillary beds) throughout the body
Exchange of substances across capillary walls
1. Oxygen and nutrients diffuse out of the capillary and into the tissue fluid
2. Wastes (carbon dioxide) diffuse into the capillary
3. Some water leaves the capillaries, and excess is picked up by lymphatic vessels
Veins and venules
Have the same three layers as arteries, but there is less smooth muscle and connective tissue
Veins have valves, which allow blood to flow toward the heart when open and prevent blood from flowing backward when closed
Veins act as a blood reservoir
The cornea of the eye is nearly free of capillaries
How the cornea obtains nutrients
By diffusion from the tears on the outside surface, and from the fluids on the inside surface
Capillaries play an important role in homeostasis by regulating the body systems by exchanging water, wastes, and nutrients across their membranes between the blood and the tissues
How capillary beds open and close
1. Only certain capillary beds are open at any given time
2. After eating, capillary beds that serve the digestive system are open, and those that serve the muscles are mostly closed
3. Sphincter muscles relax to open the bed and allow blood flow
4. Sphincter muscles contract to close the bed and prevent blood flow
5. When the bed is closed, blood flows through anastomoses (arteriovenous shunts) directly from arterioles to venules, bypassing the bed
Capillary beds need to open and close to divert blood to the areas that are working and require more oxygen and nutrients and waste removal at any one time
Recent evidence suggests that the blood supply to the brain is maintained under most physiological conditions, including ingesting a heavy meal, and that hormones released by the digestive tract may instead be the cause of "postprandial somnolence" (being sleepy after eating)
Blood
A liquid connective tissue that has many different functions: transports nutrients, wastes, and hormones; regulates body temperature; regulates blood pressure; protects the body against invasion by disease-causing pathogens; clotting mechanisms protect the body against loss of blood
Composition of blood in a test tube
Upper layer: plasma (liquid portion of blood)
Lower layers: formed elements (white blood cells, platelets, red blood cells)
Plasma
The liquid portion of blood that contains a variety of inorganic and organic substances dissolved or suspended in water
Components of plasma
Water
Proteins
Glucose
Lipids
Electrolytes
Hormones
Waste products
Sinoatrial Node: The SA node (the pacemaker located in the upper dorsal wall of the atrium) initiates the
heartbeat. It sends out a stimulus (an excitation electrical impules, every 0.85s), which causes
the atria to contract. It also stimulates the AV node
b) Atrioventricular node
Th SA stimulus reaches the AV node in the base of the right atrium near the septum. The AV
node signals the ventricles to contract. Impulses pass down the two branches of the
atrioventricular bundle to the Purkinje fibres, and thereafter the ventricles