Antipyretic - fever-blocking, thermoregulatory center of the hypothalamus
Analgesic - pain-blocking, it inhibit the synthesis of prostaglandin
SALICYLATE - Widely used drugs for treating inflammatory condition
Aspirin - platelet aggregation, inhibiting the synthesis of thromboxane (5-30 mins)
It inhibit the synthesis of prostaglandin.
It blocks two enzymes
NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
COX 1 (Cyclooxygenase-1 ) - present in all tissues, involved in many body functions: blood clotting, protecting the stomach lining, maintaining Na and H2O balance in the kidneys. Important for Homeostasis
COX 2 (Cyclooxygenase-2) - site of trauma or injury
Fenoprofen
Ibuprofen
Ketoprofen
Naproxen
COX 1 Inhibitors
Diclofenac
Etodolac
Indomethacin
Acetic Acid
Meclofenamate
Mefenamic Acid
Fenamates
Meloxicam
Piroxicam
Oxicam Derivative
Celecoxib
COX 2 Inhibitors
Tylenol
Treat moderate to mild pain and fever
for pedia
thermoregulatory cells in the hypothalamus to cause sweating and vasodilation.