ANTI-INFLAMMATORY

Cards (26)

  • It is a mechanism of action that protects the body from injury and pathogens.
    It employs a variety of potent chemical mediators to produce the reaction that helps to destroy pathogens and promote healing.
    It produces signs and symptoms of a disease.
    It may lead to chronic condition and can result to damage to the body.
    INFLAMMATORY PROCESS
  • PAIN - Physical discomfort or suffering caused by injury or illness.
    • NOCICEPTIVE PAIN
    • NEUROPATHIC PAIN
    • IDIOPATHIC PAIN
    TYPES OF PAIN
  • ACUTE PAIN - ⇧Hear Rate, Respiration, Blood Pressure
  • CHRONIC PAIN - ⇩Hear Rate, Respiration, Blood Pressure
    • ONSET
    • DURATION
    • QUALITY
    • LOCATION
    • DEPTH
    • SEVERITY
    PAIN ASSESSMENT
  • ASPIRIN
    BALSALAZIDE
    CHOLINE
    MAGNESIUM
    TRISALICYLATE
    MESALAMINE
    OLSALAZINE
    SALSALATE
    SALICYLATES
  • FENOPEROFEN
    IBUPROFEN
    KETOPROFEN
    NAPROXEN
    COX 1 Inhibitors
  • COX 2 Inhibitors - CELECOXIB
  • FENAMATES - ▪ MECLOFENAMATE & MEFENAMIC ACID
  • OXICAM - ▪ MELOXICAM & PIROXICAM
  • COX 1 Inhibitor
    COX 2 Inhibitors
    FENAMATES
    OXICAM
    ACETIC ACID
    NSAIDS
  • DICLOFENAC
    ETODOLAC
    INDOMETHACIN
    KETOROLAC
    NABUMETONE
    TOLMETI
    ACETIC ACID
  • Antipyretic - fever-blocking, thermoregulatory center of the hypothalamus
  • Analgesic - pain-blocking, it inhibit the synthesis of prostaglandin
  • SALICYLATE - Widely used drugs for treating inflammatory condition
  • Aspirin - platelet aggregation, inhibiting the synthesis of thromboxane (5-30 mins)
  • It inhibit the synthesis of prostaglandin.
    It blocks two enzymes
    NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
  • COX 1 (Cyclooxygenase-1 ) - present in all tissues, involved in many body functions: blood clotting, protecting the stomach lining, maintaining Na and H2O balance in the kidneys. Important for Homeostasis
  • COX 2 (Cyclooxygenase-2) - site of trauma or injury
  • Fenoprofen
    Ibuprofen
    Ketoprofen
    Naproxen
    COX 1 Inhibitors
    • Diclofenac
    • Etodolac
    • Indomethacin
    Acetic Acid
    • Meclofenamate
    • Mefenamic Acid
    Fenamates
  • Meloxicam
    Piroxicam
    Oxicam Derivative
  • Celecoxib
    COX 2 Inhibitors
    • Tylenol
    • Treat moderate to mild pain and fever
    • for pedia
    • thermoregulatory cells in the hypothalamus to cause sweating and vasodilation.
    ACETAMINOPHEN