lab quiz 12

• Agglutinins


  Substances located in the blood that cause agglutination (clumping) of red blood cells
• Blood typing


  Determining the presence of agglutinogens on the red blood cells
• Determining blood type


  Use Anti-A, Anti-B, and Anti-Rh to test the sample
• Coagulation


  Process of forming a blood clot
• Agglutination


  Interaction between antigen and antibody
• Agglutinogens on RBC and Agglutinins in Plasma for different blood types

  • A- (A, anti-B, anti-D)
  • B+ (B, anti-A)
  • AB- (A, B, anti-D)
  • O+ (D, anti-A, anti-B)
• Hematocrit


  Percentage of whole blood occupied by red blood cells
• Hematocrit


  Relates to oxygen carrying capacity of the blood
• Normal hematocrit does not always mean normal oxygen carrying capacity
• Polycythemia vera


  • Increased red blood cells
  • Increased blood viscosity
  • Decreased oxygen delivery to extremities and capillaries
• Reasons for low hematocrit

  • Anemia
  • Leukemia
  • Low red blood cell production
• Fibrin


  Insoluble protein involved in coagulation
• Coagulation in non-heparinized capillary tube

  Poke exposes collagen, starts intrinsic pathway
• Aspirin


  Anti-coagulant that inhibits thromboxin A2 production and platelet plug formation