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Organic synthetic routes
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Cards (26)
Alkene → poly(alkene)
Conditions:
High pressure
,
catalyst
Alkene → dihalogenoalkane
Reagents:
Br2
or
Cl2
Conditions:
Room temperature
Mechanism:
Electrophilic Addition
Dihalogenoalkane → diol
Reagents:
KOH(aq)
Conditions:
Heat under reflux
Mechanism:
Nucleophilic Substitution
Alkene → halogenoalkane
Reagents:
HBr
or
HCl
Conditions:
Room temperature
Mechanism:
Electrophilic Addition
Alkane → halogenoalkane
Reagents:
Br2
or
Cl2
Conditions:
UV light
Mechanism:
Free Radical Substitution
Halogenoalkane → alkene
Reagents:
KOH alcoholic
Conditions:
Heat under reflux
Mechanism:
Elimination
Alcohol → alkene
Reagents:
Conc H2SO4
or
Conc H3PO4
Mechanism:
Elimination
,
dehydration
Alkene → alcohol
Step 1:
Reagents:
H2SO4
Mechanism:
Electrophilic Addition
Step 2:
Reagents:
H2O warm
Reaction:
Hydrolysis
Halogenoalkane → alcohol
Reagents:
KOH(aq)
Conditions:
Heat under reflux
Mechanism:
Nucleophilic Substitution
Alcohol → aldehyde
Reagents:
K2CR2O7/H+
Conditions:
Heat
and
distill
Reaction:
Partial Oxidation
Alcohol → ketone
Reagents:
K2CR2O7/H+
Conditions:
Heat
Reaction:
Oxidation
Aldehyde → Carboxylic acid
Reagents:
K2CR2O7/H+
Conditions:
Heat under reflux
and
excess oxidising agent
Reaction:
Oxidation
Aldehyde/Ketone → hydroxynitrile
Reagents:
KCN
and
H2SO4
Mechanism:
Nucleophilic Addition
Aldehyde → alcohol
Reagents:
NaBH4
Reaction:
Reduction
Mechanism:
Nucleophilic Addition
Ketone → alcohol
Reagents:
NaBH4
Reaction:
Reduction
Mechanism:
Nucleophilic Addition
Carboxylic acid → ester
Reagents:
Alcohol
and
H2SO4
Conditions:
Heat
Reaction:
esterification
Alcohol → ester
Reagents:
Carboxylic acid
and
H2SO4
Conditions:
Heat
Reaction:
Esterification
Acyl chloride/Acid anhydride → carboxylic acid
Reagents:
H2O
Conditions:
Room temperature
Mechanism:
Nucleophilic addition/elimination
Acyl chloride/Acid anhydride → ester
Reagents:
Alcohol
Conditions:
Room temperature
Mechanism:
Nucleophilic addition/elimination
Acyl chloride/Acid anhydride → primary amide
Reagents:
NH3
Conditions:
Room temperature
Mechanism:
Nucleophilic addition/elimination
Acyl chloride/Acid anhydride → secondary amide
Reagents:
Primary amine
Conditions:
Room temperature
Mechanism:
Nucleophilic addition/elimination
Halogenoalkane → nitrile
Reagents:
KCN
in
ethanol/water
Conditions:
Heat under reflux
Mechanism:
Nucleophilic Substitution
Halogenoalkane → primary amine
Reagents:
Alcoholic NH3
Conditions:
Heat under pressure
Mechanism:
Nucleophilic substitution
Nitrile → primary amine
Reagents:
LiAlH4
in
ether
Reaction:
Reduction
Primary amine → secondary/tertiary amine or quaternary salt
Reagents:
Halogenoalkane
Mechanism:
Nucleophilic Substitution
Primary amine → Secondary amine
Reagents:
Acyl chloride
Conditions:
Room temperature
Mechanism:
Nucleophilic addition/elimination