1. Information is passed down the axon of the neuron as an electrical impulse (action potential)
2. Action potential reaches the end of the axon and needs to be transferred to another neuron or tissue, by crossing the synaptic gap
3. Synaptic vesicles in the axon terminal contain neurotransmitters
4. Electrical (nerve) impulse (action potential) stimulates the release of the neurotransmitters from the synaptic vesicles
5. Neurotransmitters carry the signal across the synaptic gap and bind to receptor sites on the postsynaptic cell which then become activated