Other Blood Groups

• What blood group consists of three loci system?


  MNSs U
• What is the chromosome no. where MNSs U blood group is located?


  4
• True or False: MNSs U is not very well-developed at birth.


  false
• What component of RBC is MN associated with?


  glycophorin a
• In what testing is MNS antigen important?


  paternity
• It is phenomenon whereby an antibody reacts more strongly with a red cell carrying a double dose than with a red cell carrying a single dose.


  dosage effect
• It is an antibody that can be seen in renal patients who are dialyzed with equipment sterilized with formaldehyde.


  anti-n
• It is a blood group system that is composed of 3 antigens and 5 phenotypes.


  p blood group system
• Where is P Blood Group System located?

  chromosome 22
• True or False: The P1 and P2 are analogous to the A1 and A2 of the ABO system.


  true
• It is an antibody associated with paroxysmal cold hemoglobinuria.


  anti-p
• It is an antibody associated with spontaneous abortions in early pregnancy.


  anti-pp1 pk
• True or False: Adults with Bombay phenotype have the greatest amount of “I” antigens on their RBC.


  true
• During how many months of life in infant does “I” slowly decreases?


  18
• Patients with what bacterial infections may develop strong cold agglutinins with auto anti-I specificity?


  mycoplasma pneumoniae
• This blood group system are controlled by two independent genes; one is located on X chromosome and the other is located on an autosome (chromosome #7).


  kell blood group
• These are found only on red cells, are well-developed at birth and are not destroyed by enzymes.


  kell antigen
• It is the most common antibody seen in blood bank.


  anti-k
• What phenotype is rare and with decreased “Kell”

  system antigen expression and abnormal red

  cell morphology?

  mcleod
• This blood group is found in chromosome no. 1.

  duffy
• What are the two antigens that are easily destroyed by common proteolytic enzymes?


  fya and fyb
• What immunoglobulin react best at the AHG phase?


  IgG
• Where is Kidd Blood Group System located?


  chromosome 18
• At what temperature can Jka and Jkb inactived?


  56°C
• What blood group system is closely linked with the secretor locus?


  lutheran
• This antibody is associated with transfusion reactions.


  Anti-Lub
• What blood group is associated with HTLAs (high titer, low avidity antibodies)?


  chido/rogers
• What are the blood groups associated with sector genes?


  lewis, lutheran, abh
• What blood groups are inactivated by proteolytic enzymes?


  duffy, mnss u, xga
• What blood groups that do not store well (labile antigens)?


  kidd, duffy, htlas
• What blood groups had antigens that are poorly-developed at birth?


  lewis, p, i, lutheran
• Whi discovered the “MNSs U” Blood Group System?


  landsteiner and levine
• True or False: MNSs U is not found in body fluids and secretions.


  true
• What component of RBC is Ss associated with?


  glycophorin b
• It is considered as high frequency antigen?


  U
• What is Anti-PP1 Pk originally called?


  tja
• Whered does “I” Blood Group System loctaed?


  chromosome 6
• True or False: Anti-PP1 Pk may not be demonstrated in vitro hemolysis.


  false
• What disease is associated with much greater “I” activity on RBC than control cord cells?

  hereditary erythroblastic multinuclearity with positive acidified serum (hempas)
• What antibody is only detectable at 4°C?


  anti-i