blood banking midterms

Cards (74)

  • As defined by the ISBT, a blood group system “consists of one or more antigens controlled at a single gene locus, or by two or more very closely linked homologous genes with little or no observable recombination between them
  • Each system is genetically distinct. To date, there are 30 blood group systems and most have antithetical antigens (Ex K and k antigen)
  • Blood group collections are antigens that have a biochemical, serologic, or genetic relationship but do not meet the criteria for a system. Antigens classified as a collection are assigned a 200 number.
  • All remaining RBC antigens that are not associated with a system or a collection are catalogued into the 700 series of low-prevalence antigens or the 901 series of high-prevalence antigens
  • NUMBER: 001 NAME: ABO CHROMOSOMAL LOC: 9q NUMBER OF ANTIGENS: 4
    • NUMBER: 002 NAME: MNS
  • MNS GENE NAME ISBT: GYPA,GYPB (GYPE)
  • MNS CHROMOSOMAL LOCATION: 4q
  • MNS CD NUMBERS: CD235a (GPA) CD235b (GPB)
  • NUMBER: 003 NAME: P1PK
  • P1PK GENE NAME ISBT: A4GALT
  • P1PK CHROMOSOMAL LOC: 22q
  • P1PK NO. OF ANTIGENS: 3 CD NUMBERS: CD77
  • NUMBER 004: Rh
  • Rh GENE NAME ISBT: RHD, RHCE
  • RH CHROMOSOMAL LOCATION: 1p
  • Rh no. of antigen: 55
  • RH CD NUMBER: CD240
  • NUMBER: 005:: NAME: LUTHERAN
  • LUTHERAN SYMBOL: LU ; GENE NAME ISBT: BCAM
  • LU CHROMOSOMAL LOC: 19q
  • LU: BCAM; NO. OF ANTIGENS: 24 ; CD NUMBERS CD239
  • NUMBER: 006 ; NAME: KELL ; SYMBOL KEL
  • KEL CHROMOSOMAL LOC: 7q
  • KEL NO. OF ANTIGENS: 36 ; CD NUMBERS: CD238
  • NUMBER: 007 ; NAME: LEWIS ; SYMBOL: LE
  • NUMBER: 007 ; NAME: LEWIS ; SYMBOL: LE
  • LE GENE NAME ISBT: FUT3 ; CHROMOSOMAL LOC:19p
  • LE NO. OF ANTIGENS: 6 ; CD NUMBER: NONE
  • NUMBER: 008 ; NAME: DUFFY ; SYMBOL; FY
  • FY GENE NAME ISBT: ACKR1 (formerly known as DARC)
  • FY CHROMOSOMAL LOC: 1q
  • FY NO. OF ANTIGENS: 5 ; CD NUMBERS: CD234
  • NUMBER: 009 ; NAME: KIDD ; SYMBOL: JK
  • JK GENE NAME ISBT: SLC14A1 ; CHROMOSOMAL LOC: 18q
  • JK NO. OF ANTIGENS: 3 ; CD NUMBERS: NONE
  • NUMBER: 010 ; NAME: DIEGO ; GENE NAME ISBT: SLC4A1
  • NUMBER: 010 ; NAME: DIEGO ; SYMBOL: SLC4A1
  • SLC4A1 CHROMOSOMAL LOC: 17q ; NO. OF ANTIGENS: 22 ; CD NUMBERS: CD 233
  • Lewis System (LE) ISBT (007)