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sex linkage and recombination
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Cards (15)
Recombination
Homologous pairs of chromosomes exchange
genes
Increases genetic
diversity
How are sex-linked traits
inherited?
1. Human Chromosomes
Human
chromosomes
Sex linkage
Inheritance of genes located on the
sex chromosomes
-
X chromosome
Sex-linked traits
Hemophilia
(bleeding disorder)
Ocular Albinism
Webbed Toes
Hypertrichosis
(hairy ears)
Sex-influenced traits
Breast
size
Pattern
Baldness
Risk of
osteoporosis
Muscle
mass
Body
Hair
Distribution
Sex-limited traits
Genes that can be found in both sexes, but only one sex has it on their
phenotype
, controlled by
autosomal
genes
Pedigree analysis
1. Observe/analyze how
trait
runs in families
2. Identify mode of
inheritance
of
traits
3. Determine
genotype
4. Determine risk of
recurrence
Pedigree
Pictorial representation of how a trait is
transmitted
among the members of the family
Autosomal dominant inheritance
Affected individual manifests corresponding trait
Affected individual should have at least
1 affected parent
Tendency to
not
skip
generations
Autosomal dominant inheritance
Achondroplasia
Marfan
syndrome
Autosomal recessive inheritance
Individuals have
alleles
but might not express it
Can have both
unaffected
parents (carriers)
Can skip
generations
Autosomal recessive inheritance
Cystic Fibrosis
Sickle cell anemia
What are the 1st to 22nd pairs of human chromosome are called?
Autosomes
What is the 23rd human chromosome called?
sex chromosome