sex linkage and recombination

Cards (15)

  • Recombination
    • Homologous pairs of chromosomes exchange genes
    • Increases genetic diversity
  • How are sex-linked traits inherited?
    1. Human Chromosomes
  • Human chromosomes
  • Sex linkage
    Inheritance of genes located on the sex chromosomes - X chromosome
  • Sex-linked traits
    • Hemophilia (bleeding disorder)
    • Ocular Albinism
    • Webbed Toes
    • Hypertrichosis (hairy ears)
  • Sex-influenced traits
    • Breast size
    • Pattern Baldness
    • Risk of osteoporosis
    • Muscle mass
    • Body Hair Distribution
  • Sex-limited traits
    Genes that can be found in both sexes, but only one sex has it on their phenotype, controlled by autosomal genes
  • Pedigree analysis
    1. Observe/analyze how trait runs in families
    2. Identify mode of inheritance of traits
    3. Determine genotype
    4. Determine risk of recurrence
  • Pedigree
    Pictorial representation of how a trait is transmitted among the members of the family
  • Autosomal dominant inheritance
    • Affected individual manifests corresponding trait
    • Affected individual should have at least 1 affected parent
    • Tendency to not skip generations
  • Autosomal dominant inheritance
    • Achondroplasia
    • Marfan syndrome
  • Autosomal recessive inheritance
    • Individuals have alleles but might not express it
    • Can have both unaffected parents (carriers)
    • Can skip generations
  • Autosomal recessive inheritance
    • Cystic Fibrosis
    • Sickle cell anemia
  • What are the 1st to 22nd pairs of human chromosome are called?
    Autosomes
  • What is the 23rd human chromosome called?
    sex chromosome