PROTEINS

• N-terminal end – amino group free
• C-terminal end – carboxyl group free
• All plasma proteins except Gamma-globulins are synthesised in the liver.
• prealbumin is also known as transthyretin
• prealbumin migrates ahead of albumin, rich in tryptophan, Transport protein of thyroid hormones and Binds with retinol-binding protein to form a complex that transports retinol
• decreased prealbumin - sensitive marker of poor protein nutritional status
• troponin - Bind to the thin filaments of striated muscles
• gc-globulin : Group-specific Component/Vitamin D-binding protein
• alpha 2 macroglobulin Found principally in the intravascular spaces , Inhibits proteases
• transferrin : Transports iron, can carry it to cells and prevents loss of iron through the kidney
• hemopexin - Removes circulating heme
• other word for transferrin is Siderophilin
• HDL – alpha-globulin
• LDL – beta-globulin
• VLDL – pre-beta globulin
• alpha 1 acid glycoprotein is also called as orosomucoid
• alpha 1 - antitripsin : Acute-phase reactant

  Neutralize trypsin-like enzyme that can cause

  hydrolytic damage to structural protein