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Mariebel B. De Sagun
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Mitosis
A type of cell division in which the nucleus of the cell divides into 2 nuclei with identical genetic material
Mitosis
Resulting in 2 diploid (2n) daughter cells after division of a diploid (2n) parent cell containing two sets of chromosomes
Human body cell contains 46 chromosomes
Occurs only in eukaryotes and used by multicellular organisms for growth, development, repair, and asexual reproduction
Stages of Mitosis
1. Prophase
2. Metaphase
3. Anaphase
4. Telophase
5. Cytokinesis
Prophase
1. Chromatids coil and become visible
2. Each chromosome contains 2 identical sister chromatids
3. Nuclear membrane dissolves and spindle fibers form
4. Centrioles migrate to opposite poles and nucleolus disappears
Metaphase
1. Chromosomes align at the metaphase plate
2. Spindle fibers connect each chromosome to the centrioles at opposite poles
Anaphase
1. Proteins binding sister chromatids divide
2. Separated chromosomes move to opposite poles due to shortening of spindle fibers
Telophase
1. Nuclear membrane reforms around chromosomes which start to uncoil
2. Spindle fibers dissolve
3. Each chromosome in daughter cell is one chromatid
4. Cytokinesis begins
Cytokinesis
1. In animal cells, cleavage furrow forms at exterior and moves inward
2. In plant cells, cell plate forms at middle and moves outward
Meiosis
A type of cell division used by multicellular organisms to form reproductive cells (gametes) with half the number of chromosomes
Meiosis
Produces 4 haploid (n) daughter cells from 1 diploid (2n) parent cell
Meiosis I is a reductional division, Meiosis II is an equational division
Stages of Meiosis
1. Prophase I
2. Metaphase I
3. Anaphase I
4. Prophase II
5. Metaphase II
6. Anaphase II
7. Telophase II
Prophase I
1. Chromosomes coil and shorten
2. Nuclear envelope disintegrates
3. Homologous chromosomes pair by synapsis
4. Crossing-over may occur
Metaphase I
1. Paired homologous chromosomes align at metaphase plate
2. Chromosomes attached to spindle fibers
Anaphase I
Homologous chromosomes separate and move to opposite poles
Prophase II
1. Nuclear membrane disintegrates
2. New spindle fibers form
Metaphase II
Chromosomes align at metaphase plate, attached to spindle fibers at centromeres
Anaphase II
Each chromosome divides into sister chromatids which move to opposite poles
Telophase II
1. Nuclear membrane reforms around each set of chromosomes
2. Spindle fibers disintegrate
3. Cytokinesis occurs
Stages of Cell Cycle
Interphase (G1, S, G2)
Mitosis (Prophase, Metaphase, Anaphase, Telophase, Cytokinesis)
Gregor Johann Mendel
Austrian monk, biologist, meteorologist, and mathematician known as the "Father of Modern Genetics"
Mendel studied the pattern of inheritance using the garden pea Pisum sativum and experimented on almost 30,000 pea plants
Reason Mendel chose pea plants
They were easily grown and raised in the monastery garden, and each plant has both male and female sexual organs
7 contrasting traits Mendel studied in pea plants
Seed form (round/wrinkled)
Seed color (yellow/green)
Pod form (inflated/constricted)
Pod color (green/yellow)
Flower color (purple/white)
Flower position (axial/terminal)
Stem length (tall/short)
Genetic Terminology
Alleles - alternative forms of a gene
Chromosome - linear or circular DNA strand containing genes
Diploid - organism with two copies of each chromosome
DNA - Deoxyribonucleic acid, the molecule that carries genetic information
Gene - the fundamental unit of heredity, a specific section of DNA