Chemo drugs

• What is vincristine used for?

  Chemotherapy protocol to treat lymphoma.
• MOA- Vincristine?


  Causes metaphase arrest by interfering with microtubule formation and preventing formation of the nuclear spindle. Leading to cell death.
• Use of cyclophosphamide?


  To treat mammary tumours, sarcomas in lungs.
• what protocol can cyclophosphamide be used in?


  COP protocol to treat lymphoma. Combined with vincristine and prednisolone.
• MOA- Cyclophosphamide?


  Alkylating agent, it metabolites by interfering with DNA synthesis and function and RNA transcription. Causes DNA strands to break and act on all stages to cause cell death.
• What is prednisolone used to treat?

  Lymphoma, administered orally.
• MOA- Prednisolone?


  Is a corticosteroid which possess anti-inflammatory effects. Has immunosuppressive properties and inhibits mitosis and protein synthesis in sensitive lymphocytes.