Polyomaviridae

Cards (4)

  • Polyomaviridae
    • Small, non enveloped, circular double stranded DNA virus 
    • Latent states are in the kidney and B lymphocytes 
    • Associated with immunocompromised individuals 
    • Bk virus is associated hemorrhagic cystitis and JC virus is associated with disease or progressive multifocal leukoencephalopathy 
    • MC virus is associate with Merkel Cell Carcinoma 
    • BK and JC - are initials of patients in where they discovered the virus
  • BK virus (Polyomavirus hominis 1)
    Causes mild or asymptomatic infection in children
  • JC virus (Polyomavirus hominis 2)
    May cause progressive multifocal leukoencephalopathy 
    • One of the leading cause of death for those with HIV and persistent UTI 
    • Patient develops CNS, white matter damage
  • Viruses under Polyomaviridae
    BK Virus
    JC Virus