HHV-8

• Rhadinovirus/ Gamma herpes virus (HHV-8)

  AKA 

  Rhadinovirus/Gamma herpes virus

  Kaposi’s sarcoma assoc. herpes virus 

  • Assoc. w/ Kaposi sarcoma 
  • Causative agent of kaposi sarcoma
  • Assoc. w/ HIV/AIDS & immunocompromised
  • Infects lymphocytes and epithelial/endothelial cells

  
• MOT of HHV-8 (Rhadinovirus/gamma herpes virus)

  Sexual activity

  Esp. in homosexual males
• Assoc. diseases w/ Kaposi's sarcoma assoc. herpes virus (HHV-8)

  Hematologic malignancies

  • Primary effusion lymphoma
  • Multicentric Castleman’s disease (MCD)
  • MCD-related immunoblastic/plasmablastic lymphoma 
  • Oral hairy leukoplakia