transports blood from the RV, through the lungs, and back to the LA
Pulmonary vessels
transport blood through all parts of the body from the left ventricle and back to the right atrium
Systemic vessels
Functions of the circulatory system
Carries blood; Exchanges nutrients, waste products and gases with tissues; Transport substances; Help regulate BP; Directs blood flow to tissues
They diffuse from blood vessels to cells in all areas of the body
Nutrients and O2
They diffuse from the cells, where they are produced, to blood vessels
Waste products and CO2
Three main types of blood vessels
Arteries, Capillaries, and Veins
They carry blood away from the heart
Arteries
They pump blood from the heart into large, elastic arteries that branch repeatedly to form many progressively smaller arteries
Ventricles
Although the arteries form a continuum from the largest to the smallest branches, they are normally classified as
Elastic arteries, muscular arterioles, or arterioles
It is the most common blood vessel type where blood flows from arterioles into this.
Capillaries
Where do most of the exchange that occurs between the blood and interstitial spaces occurs?
Across the wall of the capillaries
They are vessels that carry blood toward the heart from the capillaries
Veins
How are veins classified as?
Venules, small veins, medium/large veins
The internal lining of simple squamous epithelial cells which is continuous with the endocardium of the heart
Endothelium
What does the capillary wall primarily consist of which rests on a basement membrane?
Endothelial cells
These are scattered along the length of the capillary that is closely associated with the endothelial cells
Pericapillary cells
How many in diameter does a capillary range from?
7-9 micrometer
Approx. how long are capillaries?
1mm
How do RBCs flow through most capillaries?
Single file and are folded as they pass thru smaller-diameter capillaries
How are capillaries classified as depending on their diameter and permeability?
Continuous, fenestrated, or sinusoidal
They are approximately 7–9 μm in diameter, and their walls exhibit no gaps between the endothelial cells; Less permeable
Continuous capillaries
Where do continuous capillaries exist?
Muscle, nervous tissue, and many other locations
These capillaries are in tissues with where capillaries are highly permeable such as the intestinal villi, ciliary processes of the eyes, choroid plexuses of the CNS, and glomeruli of the kidneys
Fenestrated Capillaries
These are areas approximately 70–100 nm in diameter in which the cytoplasm is absent and the plasma membrane consists of a porous diaphragm that is thinner than the normal plasma membrane
Fenestrae
They are larger in diameter capillaries than the other two and their basement membrane are less prominent/completely absent; Fenestrae are larger and gaps can exist in endothelial cells
Sinusoidal capillaries
Where do most sinusoidal capillaries occur?
Endocrine glands
are large-diameter sinusoidal capillaries which are common in the liver and bone marrow; basement membrane is often sparse & missing; cells can readily move across walls in the endothelial cells
Sinusoids
are similar in structure to the sinusoidal capillaries but even larger in diameter; exist primarily in the spleen; Large gaps between endothelial cells
Venous sinuses
How do substances cross capillary walls?
By diffusing through/between endothelial cells or through fenestrae
Where do larger water soluble substances must pass through?
Through fenestrae/gaps between endothelial cells
They supply blood to each capillary network
Arterioles
These are vessels with isolated smooth muscle cells along their walls, where blood flows from arterioles to this
Metarterioles
From metarterioles, blood flow to this vessel that extends in a relatively direct fashion from a metarteriole to a venule
Thoroughfare channel
They are smooth muscle cells located at the origin of the branches that regulate blood flow of branches from several capillaries from the thoroughfare channels
Precapillary sphincters
The ends of capillaries closest to the arterioles
Arterial capillaries
The ends closest to venules
Venous capillaries
They are more numerous and more extensive in highly metabolic tissues, such as in the lungs, liver, kidneys, skeletal and cardiac muscle
Capillary networks
TRUE OR FALSE: Capillary networks in the dermis of skin have less thoroughfare channels than capillary networks in cardiac or skeletal muscle