18th and 19th century (1700-1900)

• spontaneous generation


  idea of cause - that decay caused microbes to generate
• microscope improves


  1850
• louis pasteur published germ theory that bad microbes cause disease


  1861
• robert kok used pasteur work and found microbe also cause disease like TB and cholera


  1882
• koch discovered agar jelly
• florence nightingale went to crimean way 1854 - 56, 


  made a training shcool for nurses
• history of anaesthetics


  1844 - laughing gas

  1846 - ether

  1847 - chloroform - james simpson
• 1861 - joseph lister uses carbolic acid as antiseptic

  1865 - soaks instruments and bandages in it


  decreases infection
• 1875 public health act, compulsory

  no longer lasseiz faire

  • clean water, sewers,
• first public health act


  1848
• edward jenner


  1790s - smallpox vaccine

  lots of opposition from doctors and church

  1979 WHO smallpox wiped out
• cholera epidemic


  1848-49
• great stink = new sewer system 


  1875
• 1854


  john snow and cholera