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Year 1 Semester 2
FMI
viruses
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Cards (33)
reoviridae family
RNA double stranded
, rotavirus, causes
gastroenteritis
caliciviridae family
RNA, Hep-E, norovirus, sapovirus, causes viral gastroenteritis
astroviridae family
RNA, astrovirus, causes viral gastroenteritis
adenoviridae family
DNA, adenovirus, causes viral gastroenteritis
nucleic acid for hepatitis A
RNA
nucleic acid for hepatitis E
RNA
nucleic acid for hepatitis B
DNA
nucleic acid for hepatitis C
RNA
how are hepatitis A and E acquired?
faecal oral route, contaminate food and water, zoonotic
how are hepatitis B and C acquired?
blood borne
what hepatitis viruses have vaccines?
A + B, E in china
delta hepatitis
small enveloped RNA virus, cannot have unless you have Hep-B as it needs HBV to replicate
what antiviral would you take for Hep-E?
Ribavirin
measles is a RNA virus, humans are the only natural host
measles are transmitted by direct contact with infectious droplets
clinical features of measles
initial
viraemia
with elevated temperature, miserable child,
sore
eyes, koplik spots
koplik spots
herpes simplex virus 1
orofacial lesions, alpha, sensory nerve ganglia
herpes simplex virus 2
genital lesions, alpha, sensory nerve ganglia
varicella zoster virus
chicken pox (recurs as shingles), alpha, sensory nerve ganglia
cytomegalovirus
mono, beta, lymphocytes
human herpes virus 6
roseola infantum, beta, CD4 t-cells
human herpes virus 7
roseola infantum, beta, CD4 t-cells
epstein-barr virus
infectious mono, gamma, b lymphocytes
human herpes virus 8
kaposi's sarcoma, gamma, tissues
Treatment for mucocutaneous infection (herpes 1)?
OTC topical creams containing acyclovir
treatment for herpes simplex encephalitis?
aciclovir
shingles
epstein-barr
virus
HIV
human immunodeficiency virus
HIV is a single stranded RNA virus belonging to the retrovirus family
HIV is transmitted sexually, vertically, organ donation, blood transfusion, contaminated needles
prion disease
fatal neurodegenerative disorders that come from infectious proteinaceous particles known as prions