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FNSC2002
Elderly
Calorie restriction
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Created by
Victoria Mok
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Cards (4)
Calorie restriction
Definition: Limit
energy
(calorie) intake by
25
–
30
% (e.g. 1800 vs 2400 kcal)
Also called
Energy
Restriction/
Dietary
Restriction
Energy intake
minimized
BUT
sufficient
quantities of
vitamins
,
minerals
, and other imp. nutrients (CR w/o
malnutrition
;
‘Healthy’
starving)
Increase
lifespan
in animal models
• Reprogramming of
energy
metabolism (Change
metabolic
rate
)
•
Retarding
age-related decline in
immune
function
Anti-aging effect b/c retardation of age-associated
disease
• e.g.
Renal
disease,
Cancer
,
Autoimmune
disease,
Diabetes
,
Neurodegeneration
Studies on non-human primates (Monkeys):
Ongoing
Effect on human longevity:
Unclear
(
Long
term studies required)