Calorie restriction

Cards (4)

  • Calorie restriction
    • Definition: Limit energy (calorie) intake by 2530% (e.g. 1800 vs 2400 kcal)
    • Also called Energy Restriction/ Dietary Restriction
    • Energy intake minimized BUT sufficient quantities of vitamins, minerals, and other imp. nutrients (CR w/o malnutrition; ‘Healthy’ starving)
  • Increase lifespan in animal models
    • Reprogramming of energy metabolism (Change metabolic rate)
    Retarding age-related decline in immune function
  • Anti-aging effect b/c retardation of age-associated disease
    • e.g. Renal disease, Cancer, Autoimmune disease, Diabetes, Neurodegeneration
    • Studies on non-human primates (Monkeys): Ongoing
    • Effect on human longevity: Unclear (Long term studies required)