Pharmacology

• Antiseptic

  A substance that kills or inhibits the growth of microorganisms
• Antiseptics from the group of dyes

  • methylene blue
• Halogen-containing antiseptics

  • chloramine B
• Antiseptics from the group of oxidizing agents

  • potassium permanganate
• Resorcinol

  Indication for use: skin diseases
• Brilliant green

  • Fast development of effect
• Potassium permanganate


  Indication for use: douching
• Furacilin


  Refers to antiseptics
• Mechanism of action of antiseptics

  • Protein denaturation
• Groups of drugs related to chemotherapeutic agents

  • Antibiotics
• Mechanism of antimicrobial action of penicillins

  • Violation of bacterial cell wall protein synthesis
• Antibiotics from the group of biosynthetic penicillins

  • benzylpenicillin sodium salt
• Long-acting biosynthetic penicillin


  • benzylpenicillin novocaine salt
• Ampicillin

  • Broad spectrum of antimicrobial action
• Cefotaxime


  • Broad spectrum of antimicrobial action
• Antibiotics from the carbapenem group


  • imipenem
• Antibiotics from the macrolide group

  • oleandomycin
• Antibiotics from the group of semisynthetic macrolides

  • roxithromycin
• Macrolides


  • Narrow spectrum of action, resistance of microorganisms develops slowly
• Antibiotics from the tetracycline group

  • methacycline hydrochloride
• Chloramphenicol


  Highly toxic
• Antibiotics from the aminoglycoside group

  • streptomycin
• Aminoglycosides


  Ototoxic effect
• Neomycin

  Route of administration: locally
• Polymyxin M

  Indication for use: enterocolitis
• Antibiotics from the lincosamide group

  • clindamycin
• Sulfonamide drugs

  • phthalazole
• Sulfalene

  Sulfonamide drug used for resorptive action
• Phthazine

  Sulfonamide drug that acts in the intestinal lumen
• Sulfacyl sodium

  Sulfonamide drug for topical use
• Mechanism of action of sulfonamide drugs

  • Competitive antagonists with PABA
• Sulfonamides

  Side effect: crystalluria
• Combination drug of sulfonamides with trimethoprim

  • sulfatone
• Bactrim (Biseptol)

  • Has a bactericidal effect
• Mechanism of action of fluoroquinolones

  • Inhibit bacterial enzymes (DNA gyrase)
• Synthetic antibacterial agents - derivatives of 8-hydroxyquinoline

  • nitroxoline
• Nitroxoline

  Used for urinary tract infections
• Furazolidone

  Indication for use: bacillary dysentery
• Bismuth drug used in the treatment of syphilis

  • biyoquinol
• Synthetic anti-tuberculosis drugs

  • isoniazid